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RAI HEALTH JOURNAL

AI in healthcare. With evidence.

From medicines to biobanks: research, applications and their limitations, explored through trusted sources.

Artikujt ofrohen në turqisht dhe anglisht; disa edhe në estonisht dhe polonisht.

A gloved researcher using a pipette with samples in laboratory tubes.
EnglishGenetics

AI and RNA splicing: from prediction to validation

A genetic change can alter how RNA is processed. SpliceAI and Pangolin research, ClinGen clarifications and the new SpliceAI2 announcement help explain which questions a prediction can answer.

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Two healthcare professionals reviewing a document together in a bright clinical setting.
EnglishDrug discovery

AI clinical trial matching: from prescreening to human review

Suggesting a clinical trial does not establish eligibility. The 2024 TrialGPT study and NLM’s explanations help clarify AI’s role in drug research and the limits of the evidence.

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A gloved researcher pipetting liquid into a cell culture plate in a laboratory.
EnglishBiotechnology

AI in single-cell biology: large models need independent evaluation

How useful is a model trained on millions of cells when it encounters new data? Reading scGPT alongside an independent evaluation helps separate research performance from clinical evidence.

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An adult woman positioned at an eye examination instrument in a clinic.
EnglishMedical devices

Autonomous AI in eye screening: from a model to a clinical workflow

What evidence should we read before relying on a screening system? The 2018 IDx-DR example helps separate intended use, research findings and clinical workflow.

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Two people reviewing a computer screen in a healthcare setting.
EnglishCybersecurity

Healthcare ransomware: restoring systems does not close the data investigation

Service recovery, data confidentiality and the origin of an incident are separate questions. We read an institutional disclosure alongside HHS and FDA guidance through that distinction.

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Pipette tips on an automated liquid-handling instrument in a genomics research laboratory.
EnglishVaccines

AI in cancer vaccines: from target ranking to clinical evidence

AI can help prioritise targets for personalised cancer-vaccine research. Using BigMHC as an example, we examine why predictive performance, immune response and patient benefit need separate assessment.

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An MRI scanner and examination table in an unoccupied imaging room.
EnglishBiobanks · Radiology

Imaging biobanks and AI: from MRI to research measurements

AI can turn biobank MRI scans into organ measurements and reference atlases. Why do quality control and the population represented matter in that process?

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Close-up photograph of a gloved researcher adjusting a laboratory microscope.
EnglishDigital pathology

Digital pathology AI: will the model work in another laboratory?

A research score does not guarantee the same result across laboratories. Why task, data provenance and local validation belong together when comparing pathology AI models.

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A researcher compares a DNA sequencer’s computer output with a Sanger chromatogram held beside the keyboard.
EnglishGenetics

AI genetic variant interpretation: where does a score fit in clinical evidence?

An AI variant score is not a diagnosis. Using AlphaMissense and ClinGen’s calibration research to distinguish research output, strength of evidence and clinical interpretation.

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A researcher in blue gloves examines a culture in a Petri dish at a laboratory workstation.
EnglishDrug discovery

AI antibiotic discovery: what do explainable models add?

Understanding why a molecule was selected can help researchers investigate new antibiotic candidates. Separating explainable AI, experimental evidence and the remaining steps towards clinical use.

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A researcher wearing blue gloves uses a micropipette at a laboratory bench.
EnglishBiotechnology

AI protein design: from model to laboratory

What does designing a new protein actually establish? Reading RFdiffusion and BindCraft while keeping experimental success separate from clinical benefit.

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Server cabinets lining a data centre aisle, with a management terminal showing a blank screen.
EnglishCybersecurity · Medical devices

The Stryker cyberattack: lessons for healthcare continuity

A look back at March 2026: distinguishing corporate disruption, device safety and hospitals’ dependence on suppliers.

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Close-up of the white keyboard, control knobs and dark display of an ultrasound machine
EnglishMedical devices

AI medical device updates: how do we control change?

A new model version is more than a software update. FDA and MHRA sources help explain predetermined change plans, ongoing monitoring and the information users need.

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A digital mammography unit with a transparent compression paddle in a bright imaging room
EnglishRadiology

AI in mammography: how to read the MASAI trial results

More detection, fewer readings and follow-up outcomes are different measures. We examine the 2025 and 2026 MASAI publications within the limits of their evidence.

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A vaccine vial, syringe and test tube in front of a microscope on a blue background
EnglishVaccines

AI in vaccine research: from mRNA design to clinical evidence

How should we read a design algorithm’s success? We examine LinearDesign alongside WHO’s clinical development framework and EMA’s draft quality guidance.

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Laboratory sample tubes with red and blue caps in a storage rack
EnglishBiobanks

AI in biobanks: from data quality to modelling disease risk

How can large research collections support AI? We examine data preparation, the Delphi study and the limits of model sharing using primary sources.

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A researcher wearing protective glasses and gloves uses a microscope beside a laboratory computer.
EnglishDigital pathology

AI in digital pathology: from slides to decision support

Research performance, regulatory authorization and laboratory implementation answer different questions. We read an original study alongside FDA and NCI sources.

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Two researchers examining computer data in a bright research laboratory
EnglishGenetics

AI protein structure prediction: reading confidence in genetics research

A detailed protein model does not make every region equally reliable. We distinguish research evidence, open data resources and the limits of clinical interpretation.

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EnglishDrug discovery · Biotechnology

AI drug discovery: from molecules to clinical evidence

Designing a drug candidate with AI does not establish patient benefit. We read a phase 2a study alongside EMA’s approach to evaluating AI.

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EnglishRadiology · Medical devices

AI in healthcare: examine the evidence before adoption

How do we distinguish a device’s regulatory status from a generative model’s capabilities? Two starting points from FDA and WHO sources.

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Our editorial approach: primary sources, explicit references and the limits of the evidence. AI-assisted editorial content; not individual medical advice.

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